Phospholipid 4+1 Complex
Serine, choline & inositol
Orderable
- Free of dyes
- Gluten-free
- Preservative-free as required by law
- Lactose-free
- Vegan
- Free of anti-caking and binding agents
| Price Tiers |
| from 1 Pieces | 39,95 € |
| from 3 Pieces | 35,95 € |
| from 5 Pieces | 33,95 € |
NatuGena Phospholipid 4+1 Complex – A combination of five different phospholipids: phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine, phosphatidylserine and phosphatidic acid. Contains the certified branded ingredient LeciFis® EXP lecithin. 150 vegan capsules for a 30-day supply.
- Phospholipid complex with 5 components: Contains phosphatidylcholine, -ethanolamine, -inositol, -serine & phosphatidic acid – key structural components of cell membranes
- LeciFis® EXP lecithin (non-GMO): premium lecithin from rapeseed, rich in phosphatidylcholine, phosphatidylethanolamine and phosphatidylinositol
- Inositol: Formerly known as “vitamin B8”, a component of biological membranes, particularly in the nervous syst
- Sunflower lecithin: Plant-based source of phosphatidylserine
- Produced in Germany: Exceptional purity and bioavailability for optimal nutrient uptake

What are phospholipids and why are they important?
Phospholipids, also known as lecithins, are fundamental building blocks of every cell membrane. They determine which substances can enter and leave the cell. Phosphatidylcholine and phosphatidylethanolamine, in particular, are central components of cell structure, found in both plant and animal membranes. Together, they form the flexible bilayer that surrounds every cell.
What role does inositol play in cell structures?
Inositol, previously referred to as vitamin B8 is a sugar alcohol and a natural component of cell membranes. It occurs in particularly high concentrations in the central nervous system. As part of phosphatidylinositol, it contributes to the natural diversity of phospholipids.

What makes phosphatidylserine special?
Phosphatidylethanolamines belong to the lipid group, more specifically to the phosphoglycerides. Phosphatidylserine is a phospholipid-containing component of plant cell membranes derived from serine. In this product, it is sourced from sunflower lecithin and complements the complex with another naturally occurring component.
Why does the complex include multiple lecithin sources?
The combination of LeciFis® EXP (rapeseed) and sunflower lecithin ensures a broad phospholipid profile, designed to provide a comprehensive supply of central cellular building blocks. Both sources are non-GMO and sustainably produced. Due to its lipophilic components, the Phospholipid 4+1 Complex is ideally suited for combination with fat-soluble micronutrients.
Quality
- No separating agents, binding agents or colourants
- Free from genetic engineering, nanoparticles and animal testing
- Hypoallergenic and sensitive formulations (e.g. free from lactose, soya and gluten where possible)
- Ultra-pure, plant-based coating agents (HPMC) and food-safe, light-protected containers
- Free from unwanted additives such as PEG, silicon dioxide, magnesium stearate & titanium dioxide
- Premium raw materials from pure substances
- Regular, independent testing for harmful substances
- Production in accordance with German quality standards (GMP, HACCP, ISO 9001)
Recommended Consumption
5 capsules once a day. It is best to take them at least 30 minutes before or 90 minutes after a meal, with 250 ml of still, lukewarm water or, alternatively, with a teaspoon of omega-3 oil to increase bioavailability.
Notes
Food supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children. Store in a cool, dry place away from light. Do not exceed the recommended daily intake.
Content
| Ingredients per | Daily Dose |
|---|---|
| LeciFis EXG RAP IPM | 2155 mg |
| – of which phosphatidylcholine | 754 mg |
| – of which phosphatidylinositol | 431 mg |
| – of which phosphatidylethanolamine | 366 mg |
| – of which phosphoric acid | 65 mg |
| Phosphatidylserine | 100 mg |
| Lecithin | 75 mg |
Composition
Phospholipid complex granulate LeciFis EXG RAP IPM (rapeseed), coating agent: hydroxypropyl methylcellulose (HPMC); phosphatidylserine, lecithin (sunflower).
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Read moreFAQ
Most of our capsules can be opened without any concerns. The contents can be stirred into yogurt, plant-based yogurt, applesauce, smoothies, or juice, for example.
One of the reasons we encapsulate the ingredients is to keep their sometimes intense natural taste and smell as neutral as possible. When opened, the taste and smell may therefore be more noticeable.
Did you know? Our capsules can be easily opened by gently twisting them.
Please do not open: enteric-coated capsules
For certain bacterial and enzyme products, we use enteric-coated capsules. These should not be opened, as doing so may alter the intended release profile.
These include, for example:
- Bacterial preparations, such as HistaBakt, MakroAktiv, and BactoGena 21+2
- Enzyme products, such as N-Zymarase® Intest and N-Zymarase® Inflam. Exception: N-Zymarase Komplex contains betaine HCl, which is intended to take effect in the stomach; therefore, it does not have an enteric-coated capsule shell and can be opened
- Soft capsules with liquid contents, such as omega-3 capsules, are also not intended to be opened. In this case, you can switch to the liquid oil instead.
If you have any questions, please contact our advisory team at info@natugena.de.
From the very beginning, NatuGena has used exceptionally pure, plant-based HPMC capsules in the majority of its products. HPMC stands for hydroxypropyl methylcellulose and is made from plant-based cellulose.
Unlike many HPMC capsules commonly available on the market, the coating agents we use contain no carrageenan or PEG. Although they are more expensive, they meet our high standards for a carefully selected and transparent product composition.
Our plant-based HPMC capsules are:
- 100% plant-based cellulose (HPMC)
- Carrageenan-free
- PEG-free
- Gelatin-free
- GMO-free
- Free of allergens and irritants
What types of capsule shells are used in omega-3 products?
Special softgels are required for liquid oils. Our classic omega-3 capsules therefore contain a coating made from gelatin and glycerin and are not vegan.
In our vegan omega-3 capsules made from algae oil, the coating consists of glycerin and modified cornstarch and contains no gelatin. This makes these capsules suitable for a vegan diet.
The exact composition of each coating agent is clearly listed in the ingredients list.
It All Comes Down to the Composition
Conventional capsule shells may contain technical additives—such as anti-caking agents, release agents, or binders—due to the manufacturing process. These components aren’t always immediately apparent, as certain processing aids aren’t required to be listed in the ingredients list.
Most of the NatuGena capsule products are size 00 (8,2 × 23,3 mm) to 0 (7,3 × 21,2 mm). Information on the capsule sizes of individual products can be found on the relevant product page or by contacting info@natugena.de
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|---|---|---|---|---|---|
| 9,5 × 26,1 mm | 8,2 × 23,3 mm | 7,3 × 21,2 mm | 6,6 × 19,0 mm | 6,1 × 17,3 mm | 5,6 × 15,4 mm |
| z. B. Lysin & Vitamin C, Monacolin K 3 |
z. B. Magnesia 7+1, MitochondrienAktivator 44+14, HeparAktiv |
z. B. ZellEnergie, MultiVegan, Astaxanthin |
z. B. HistaBakt, Bor, Bioaktiver B-Komplex |
not in use | z. B. Kupfer, LipoVitamine 10 000, Mangan-Komplex |
We work with the independent laboratory AgroLab, which we commission to perform microbiological and heavy metal tests.
In our microbiological testing, we measure the aerobic mesophilic plate count (total plate count), as well as the levels of Escherichia coli (E. coli), yeasts, Salmonella, molds, and staphylococci.
For heavy metals, we test for arsenic, lead, cadmium, and mercury in accordance with the limit values specified in Regulation (EU) 2023/915.
The optimal duration of use depends on the specific nutrient, your initial situation, diet, and individual requirements.
There is therefore no one-size-fits-all recommendation for how long a product should be taken. For products intended to support nutrient intake over a longer period, use over several weeks to months may be appropriate. In many cases, a period of around three months may be suitable before nutrient status and further requirements are reassessed.
In the case of diagnosed deficiencies, medical conditions, or the use of medication, the use of supplements should be individually discussed with a doctor or qualified healthcare professional.
The optimal time to take a supplement depends on the specific nutrient, individual tolerance, and the composition of the product. However, some ingredients can be particularly well suited to certain times of day or meals.
In the morning
Stimulating ingredients are often preferably taken in the morning or during the first half of the day. These include, for example:
- Coenzyme Q10
- Green tea extract
- Certain B vitamins
Especially for sensitive individuals, it may be advisable to avoid taking stimulating ingredients immediately before bedtime.
Throughout the day
For some nutrients, it may be beneficial to divide the daily amount into several doses.
Water-soluble vitamins such as B vitamins and vitamin C can be taken throughout the day.
Magnesium can also be divided into several doses rather than taking the entire daily amount at once. This may improve tolerance, particularly with higher amounts.
In the evening
Depending on the type of magnesium compound, taking it in the evening may be beneficial. Magnesium glycinate, for example, is often preferably taken in the evening.
In general, however, the best time to take a product also depends on when it is individually best tolerated and can be reliably incorporated into your daily routine.
With a meal
Some nutrients benefit from being taken together with a meal.
Fat-soluble vitamins A, D, E, and K can be taken together and ideally with a meal containing some fat.
Omega-3 fatty acids should also be taken regularly with a meal. Omega-3 oils can be combined well with fat-soluble vitamins.
Many plant-based ingredients can also be taken as part of a meal or together with omega-3 products. However, the optimal timing depends on the specific plant compound and product formulation.
Zinc can cause nausea or stomach discomfort on an empty stomach in some people. If you have a sensitive stomach, it is therefore advisable to take zinc with a meal.
Between meals
Iron is often taken separately from meals, as various foods and beverages can affect its absorption. It is particularly advisable to leave a gap between iron and:
- Coffee and tea
- Caffeinated beverages
- Milk and dairy products
- Calcium- or mineral-rich supplements
However, if you have a sensitive stomach, iron can also be taken with a meal. In this case, individual tolerance is more important than a theoretically optimal intake situation.
Enzyme supplements vary depending on their intended use: digestive enzymes are generally taken with meals. Products that are specifically intended to be taken between meals may, for example, be taken around 30 minutes before a meal. The product's specific recommended intake should always be followed.
Around exercise
Proteins and amino acids can be taken both before and after training.
If you exercise on an empty stomach, taking them around 30 minutes before training may be beneficial. If you have already eaten a protein-rich meal, you can also plan your protein intake for after training.
In general, ensuring sufficient protein intake throughout the entire day is more important than adhering to a narrow time window around your workout.
Legal notice
This product is for nutritional purposes and therefore does not affect the Heilmittelwerbegesetz (HWG). Good nutritional status is important for your general well-being. All statements made about the product describe properties and physiological effects that may naturally vary among consumers and do not represent any healing or health promises.
Responsible person for the EU
The economic operator based in the EU responsible for this product:
NatuGena GmbH, Münchener Str. 149, 85051 Ingolstadt, Germany,
+49 841 90 255 000, info@natugena.de, https://www.natugena.de





