N-Zymarase Intest
Natural enzyme complex with papain and bromelain
Orderable
- Free of dyes
- Gluten-free
- Preservative-free as required by law
- Lactose-free
- Vegan
- Free of anti-caking and binding agents
| Price Tiers |
| from 1 Pieces | 44,95 € |
| from 3 Pieces | 40,95 € |
| from 5 Pieces | 38,95 € |
NatuGena N-Zymarase Intest – Vegan enzyme complex with eight plant-based enzymes, including papain, bromelain, amylase, protease, lipase, glucoamylase, lactase and invertase. The capsules are free from dyes, release agents and binders, and are lactose-, gluten- and soy-free. 90 capsules provide a 30-day supply.
- Papain: A protein-splitting enzyme extracted from tropical papaya fruit
- Bromelain: A plant-based enzyme from the stem of the pineapple
- Protease: An enzymatically active protein
- Plant-based fermentation: All eight enzymes are obtained through natural fermentation from plant-derived raw materials
- Made in Germany: Exceptional purity and bioavailability for optimal nutrient uptake

N-Zymarase Intest is a complex of enzymes derived from plant sources, harmoniously combining bromelain and papain. It is further enriched with amylase, protease, lipase, glucoamylase, lactase and invertase. All enzymes are obtained through fermentation from plant-based raw materials.
What Makes Papain and Bromelain Special?

Papain and bromelain are protein-splitting enzymes of plant origin. Bromelain, extracted from the juice and stems of pineapples, brings a touch of tropical diversity to our enzyme complex. Originally native to South America, the fruit was particularly valued by indigenous cultures for its sweet flavour. Papain, sourced from papaya, was traditionally used by the Maya.
What Are Enzymes?
Enzymes are biocatalysts involved in a wide range of biochemical processes in the human body. They are needed in virtually all cells and play a role in natural nutrient metabolism. Enzymes such as amylase, lipase or protease are found in many foods or can be supplied through dietary supplements. The enzymes in N-Zymarase Intest are derived entirely from plant-based sources via controlled fermentation. This manufacturing method allows for a vegan formulation and provides a broad spectrum of enzymes to complement daily nutrition.
Quality
- No separating agents, binding agents or colourants
- Free from genetic engineering, nanoparticles and animal testing
- Hypoallergenic and sensitive formulations (e.g. free from lactose, soya and gluten where possible)
- Ultra-pure, plant-based coating agents (HPMC) and food-safe, light-protected containers
- Free from unwanted additives such as PEG, silicon dioxide, magnesium stearate & titanium dioxide
- Premium raw materials from pure substances
- Regular, independent testing for harmful substances
- Production in accordance with German quality standards (GMP, HACCP, ISO 9001)
Recommended Consumption
Suggested Use
1–3 capsules at the start of each meal, depending on the fat content of the meal.
Notes
Food supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children. Store closed, cool, dry and protected from light. Patients with a known allergy to pineapple and/or papaya, as well as patients with severe blood clotting disorders (e.g. haemophilia) should not take N-Zymarase® Intest. This also applies to women who are pregnant.
Content
| Ingredients per | capsule | daily dose |
|---|---|---|
| Papain (6000 USP-U/mg) | 120 mg | 360 mg |
| Bromelain (5000 FIP/g) | 120 mg | 360 mg |
| Amylase (3200 FIP) | 109 mg | 327 mg |
| Protease (115,610 FCC) | 84 mg | 252 mg |
| Lipase (100.000 U/g) | 50 mg | 150 mg |
| Glucoamylase (100000 AGU/g) | 10 mg | 30 mg |
| Lactase (10.000 ALU/g) | 10 mg | 30 mg |
| Invertase (1000 SU) | 240 μg | 720 μg |
Composition
Coating agent: hydroxypropyl methylcellulose (HMPC); bromelain, papain, amylase, protease, lipase, lactase, glucoamylase, invertase.
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The gut is much more than “just” a digestive organ—it is central to our physical, emotional, and mental health. About 80% of our immune system is located in the gut, where neurotransmitters such as serotonin are produced, and it communicates directly with our brain via the nervous system. At the same time, the gut is extremely sensitive to stress, emotional strain, and environmental toxins. A holistic view of the gut therefore means that we do not consider it in isolation, but in connection with our lifestyle, our diet, our emotions, and our own unique history.
Read moreFAQ
Which enzyme product is right for which need?
The N-Zymarase products differ primarily in terms of when they should be taken and the specific focus of their formulation. While N-Zymarase Complex and N-Zymarase Intest are designed to support digestion after a meal, N-Zymarase Fructose and N-Zymarase Gluten complement these products for specific needs. N-Zymarase Inflam holds a special place within the product family.
Which is a classic digestive enzyme product to take with a meal?
For a classic digestive enzyme complex, the following three enzymes form a good foundation:
- Bromelain for breaking down proteins
- Papain to support protein digestion
- Lipase for breaking down dietary fats
All three enzymes are included in the following products. Here’s a quick overview of the differences:
- N-Zymarase Complex - 16 enzymes plus betaine HCl - an exceptionally broad spectrum of enzymes for the digestion of carbohydrates, fats, and proteins
- N-Zymarase Intest - 8 enzymes - comprehensive digestive support with a focus on fat digestion
- Bromelain 1200 - 3 enzymes - focuses on highly active bromelain
When are N-Zymarase Gluten and N-Zymarase Fructose recommended?
N-Zymarase Fructose is a specialized product for meals where fructose is the primary focus. It contains the enzyme glucose isomerase, which converts fructose into glucose, supplemented by L-glutamine, vitamins B7 and B9, and zinc, among other ingredients; therefore, it does not replace a broad-spectrum digestive enzyme complex but rather specifically complements it.
Depending on the composition of the meal, N-Zymarase Fructose can be combined with N-Zymarase Complex or N-Zymarase Intest.
N-Zymarase Gluten is designed to enzymatically break down gluten-containing components of a meal, featuring the specific digestive enzyme “Tolerase G” for breaking down gluten, as well as fennel, caraway, and ginger. This product is not a substitute for a gluten-free diet in cases of diagnosed celiac disease.
If needed, N-Zymarase Gluten can be taken with a meal in combination with N-Zymarase Complex or N-Zymarase Intest.
How does N-Zymarase Inflam differ from digestive enzymes?
N-Zymarase Inflam is not designed as a traditional digestive enzyme complex to be taken with meals. In addition to bromelain and papain, it contains the specific enzymes trypsin and rutin. It is recommended to take N-Zymarase Inflam between meals, as this allows the enzymes to be distributed more effectively throughout the body.
NatuGena’s enzyme supplements for the digestion of proteins, carbohydrates, gluten, lactose, and other dietary challenges—for a healthy gut!
- N-Zymarase Complex: 16 enzymes plus betaine HCl—for a particularly broad spectrum of enzymes to take with meals.
- N-Zymarase Intest: 8 digestive enzymes—compact support for the digestion of protein, fat, and carbohydrates.
- Bromelain 1200: Bromelain, papain, and lipase—with a focus on highly active bromelain.
- N-Zymarase Fructose: a targeted supplement for meals containing fructose.
- N-Zymarase Gluten: with Tolerase® G for the enzymatic breakdown of gluten. Not suitable for people with celiac disease.
- N-Zymarase Inflam: bromelain, papain, trypsin, and rutin—not a traditional digestive enzyme; take between meals.
Each enzyme has its own optimal units of measurement. The enzymatic activity of bromelain, for example, is expressed in GDU (Gelatin Digesting Units). This corresponds to the ability to digest gelatin under controlled experimental conditions.
Another example is provided by the so-called HUT units (Hemoglobin Unit Tyrosine base) of the enzyme protease. These units measure the amount of enzyme required to digest a specific amount of tyrosine-releasing peptide bonds from a hemoglobin-containing substrate under standardized conditions.
To provide you with the most meaningful information possible regarding the individual enzymatic activities, the units of measurement for each enzyme may differ from one another.
Unfortunately, it is not possible to convert enzyme units into other units, as they are determined experimentally.
NatuGena’s enzyme supplements for the digestion of proteins, carbohydrates, gluten, lactose, and other challenges—generally for a healthy gut!
No. N-Zymarase Intest contains 8 enzymes, while N-Zymarase Complex contains 16 enzymes. Both contain bromelain, papain, protease, lipase, lactase, glucoamylase, and invertase, as well as a starch-digesting enzyme—amylase or diastase. N-Zymarase Complex also contains betaine HCl.
Most of our capsules can be opened without any concerns. The contents can be stirred into yogurt, plant-based yogurt, applesauce, smoothies, or juice, for example.
One of the reasons we encapsulate the ingredients is to keep their sometimes intense natural taste and smell as neutral as possible. When opened, the taste and smell may therefore be more noticeable.
Did you know? Our capsules can be easily opened by gently twisting them.
Please do not open: enteric-coated capsules
For certain bacterial and enzyme products, we use enteric-coated capsules. These should not be opened, as doing so may alter the intended release profile.
These include, for example:
- Bacterial preparations, such as HistaBakt, MakroAktiv, and BactoGena 21+2
- Enzyme products, such as N-Zymarase® Intest and N-Zymarase® Inflam. Exception: N-Zymarase Komplex contains betaine HCl, which is intended to take effect in the stomach; therefore, it does not have an enteric-coated capsule shell and can be opened
- Soft capsules with liquid contents, such as omega-3 capsules, are also not intended to be opened. In this case, you can switch to the liquid oil instead.
If you have any questions, please contact our advisory team at info@natugena.de.
From the very beginning, NatuGena has used exceptionally pure, plant-based HPMC capsules in the majority of its products. HPMC stands for hydroxypropyl methylcellulose and is made from plant-based cellulose.
Unlike many HPMC capsules commonly available on the market, the coating agents we use contain no carrageenan or PEG. Although they are more expensive, they meet our high standards for a carefully selected and transparent product composition.
Our plant-based HPMC capsules are:
- 100% plant-based cellulose (HPMC)
- Carrageenan-free
- PEG-free
- Gelatin-free
- GMO-free
- Free of allergens and irritants
What types of capsule shells are used in omega-3 products?
Special softgels are required for liquid oils. Our classic omega-3 capsules therefore contain a coating made from gelatin and glycerin and are not vegan.
In our vegan omega-3 capsules made from algae oil, the coating consists of glycerin and modified cornstarch and contains no gelatin. This makes these capsules suitable for a vegan diet.
The exact composition of each coating agent is clearly listed in the ingredients list.
It All Comes Down to the Composition
Conventional capsule shells may contain technical additives—such as anti-caking agents, release agents, or binders—due to the manufacturing process. These components aren’t always immediately apparent, as certain processing aids aren’t required to be listed in the ingredients list.
Most of the NatuGena capsule products are size 00 (8,2 × 23,3 mm) to 0 (7,3 × 21,2 mm). Information on the capsule sizes of individual products can be found on the relevant product page or by contacting info@natugena.de
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|---|---|---|---|---|---|
| 9,5 × 26,1 mm | 8,2 × 23,3 mm | 7,3 × 21,2 mm | 6,6 × 19,0 mm | 6,1 × 17,3 mm | 5,6 × 15,4 mm |
| z. B. Lysin & Vitamin C, Monacolin K 3 |
z. B. Magnesia 7+1, MitochondrienAktivator 44+14, HeparAktiv |
z. B. ZellEnergie, MultiVegan, Astaxanthin |
z. B. HistaBakt, Bor, Bioaktiver B-Komplex |
not in use | z. B. Kupfer, LipoVitamine 10 000, Mangan-Komplex |
We work with the independent laboratory AgroLab, which we commission to perform microbiological and heavy metal tests.
In our microbiological testing, we measure the aerobic mesophilic plate count (total plate count), as well as the levels of Escherichia coli (E. coli), yeasts, Salmonella, molds, and staphylococci.
For heavy metals, we test for arsenic, lead, cadmium, and mercury in accordance with the limit values specified in Regulation (EU) 2023/915.
The optimal duration of use depends on the specific nutrient, your initial situation, diet, and individual requirements.
There is therefore no one-size-fits-all recommendation for how long a product should be taken. For products intended to support nutrient intake over a longer period, use over several weeks to months may be appropriate. In many cases, a period of around three months may be suitable before nutrient status and further requirements are reassessed.
In the case of diagnosed deficiencies, medical conditions, or the use of medication, the use of supplements should be individually discussed with a doctor or qualified healthcare professional.
The optimal time to take a supplement depends on the specific nutrient, individual tolerance, and the composition of the product. However, some ingredients can be particularly well suited to certain times of day or meals.
In the morning
Stimulating ingredients are often preferably taken in the morning or during the first half of the day. These include, for example:
- Coenzyme Q10
- Green tea extract
- Certain B vitamins
Especially for sensitive individuals, it may be advisable to avoid taking stimulating ingredients immediately before bedtime.
Throughout the day
For some nutrients, it may be beneficial to divide the daily amount into several doses.
Water-soluble vitamins such as B vitamins and vitamin C can be taken throughout the day.
Magnesium can also be divided into several doses rather than taking the entire daily amount at once. This may improve tolerance, particularly with higher amounts.
In the evening
Depending on the type of magnesium compound, taking it in the evening may be beneficial. Magnesium glycinate, for example, is often preferably taken in the evening.
In general, however, the best time to take a product also depends on when it is individually best tolerated and can be reliably incorporated into your daily routine.
With a meal
Some nutrients benefit from being taken together with a meal.
Fat-soluble vitamins A, D, E, and K can be taken together and ideally with a meal containing some fat.
Omega-3 fatty acids should also be taken regularly with a meal. Omega-3 oils can be combined well with fat-soluble vitamins.
Many plant-based ingredients can also be taken as part of a meal or together with omega-3 products. However, the optimal timing depends on the specific plant compound and product formulation.
Zinc can cause nausea or stomach discomfort on an empty stomach in some people. If you have a sensitive stomach, it is therefore advisable to take zinc with a meal.
Between meals
Iron is often taken separately from meals, as various foods and beverages can affect its absorption. It is particularly advisable to leave a gap between iron and:
- Coffee and tea
- Caffeinated beverages
- Milk and dairy products
- Calcium- or mineral-rich supplements
However, if you have a sensitive stomach, iron can also be taken with a meal. In this case, individual tolerance is more important than a theoretically optimal intake situation.
Enzyme supplements vary depending on their intended use: digestive enzymes are generally taken with meals. Products that are specifically intended to be taken between meals may, for example, be taken around 30 minutes before a meal. The product's specific recommended intake should always be followed.
Around exercise
Proteins and amino acids can be taken both before and after training.
If you exercise on an empty stomach, taking them around 30 minutes before training may be beneficial. If you have already eaten a protein-rich meal, you can also plan your protein intake for after training.
In general, ensuring sufficient protein intake throughout the entire day is more important than adhering to a narrow time window around your workout.
If you need this item on a long-term basis and are interested in a discounted subscription, you can find the terms and conditions on the Product Subscription page.
Legal notice
This product is for nutritional purposes and therefore does not affect the Heilmittelwerbegesetz (HWG). Good nutritional status is important for your general well-being. All statements made about the product describe properties and physiological effects that may naturally vary among consumers and do not represent any healing or health promises.
Responsible person for the EU
The economic operator based in the EU responsible for this product:
NatuGena GmbH, Münchener Str. 149, 85051 Ingolstadt, Germany,
+49 841 90 255 000, info@natugena.de, https://www.natugena.de





