Folic Acid

Quatrefolic®
Orderable
  • Free of dyes
  • Gluten-free
  • Preservative-free as required by law
  • Lactose-free
  • Vegan
Product Type
nutritional supplement
Content
120 tablets for 120 days
Price Tiers
from 1 Pieces29,95 €
from 3 Pieces26,95 €
from 5 Pieces24,95 €
Quantity

29,95 €

incl. 7% VAT, plus shipping

Delivery time 3–5 workdays
Article number: 2018082
PPN/PZN: 11 17577761 38 (PZN = middle digits)
EAN: 4260633570820
Base price: 998,33 €per Kilogram
All prices incl. 7% VAT

NatuGena Folic Acid – Bioactive folic acid with the branded ingredient Quatrefolic®. 800 µg folic acid as methyltetrahydrofolate (5-MTHF) per daily dose in convenient tablet form. 120 tablets for a 4-month supply.

  • Vitamin B9: 800 µg bioactive folic acid per daily dose
  • Methyltetrahydrofolate (5-MTHF): The directly bioactive form of folic acid, available to the body without conversion
  • Premium branded ingredient Quatrefolic®: Enhances bioavailability through water-soluble and stable properties
  • Supports key bodily functions: Contributes to blood formation, cell division, normal homocysteine metabolism, and the reduction of tiredness and fatigue
  • Produced in Germany: Exceptional purity and bioavailability for optimal nutrient uptake
Why is 5-MTHF the best form of folic acid?

Folic acid, also known as vitamin B9, is a key micronutrient essential for many metabolic processes. NatuGena folic acid tablets contain the bioactive form methyltetrahydrofolate (5-MTHF) based on the patented Quatrefolic® formula. Unlike synthetic folic acid, 5-MTHF does not require enzymatic conversion and is immediately available to the body.
The conversion of synthetic folic acid requires a specific enzyme – dihydrofolate reductase – which transforms folic acid step by step into its active form. The sublingual form ensures particularly good absorption under the tongue. This is especially beneficial when the body’s ability to convert folic acid is impaired – for example, in older age or in cases of genetically determined enzyme deficiency.

What makes Quatrefolic® highly bioavailable?

Quatrefolic® is a patented branded ingredient from Gnosis S.p.A. that significantly improves the water solubility and bioavailability of 5-MTHF. Using a glucosamine salt, it provides a stable, directly usable form of folic acid without conversion losses. Quatrefolic® sets new standards for the quality and effectiveness of folic acid supplements.

What role does folic acid play in the body?

Folic acid contributes to normal blood formation and normal homocysteine metabolism. During pregnancy, it supports maternal tissue growth. It also contributes to the normal function of the immune system, helps reduce tiredness and fatigue, and supports normal energy metabolism. Additionally, folic acid plays a role in the process of cell division.

Quality

  • No separating agents, binding agents or colourants
  • Free from genetic engineering, nanoparticles and animal testing
  • Hypoallergenic and sensitive formulations (e.g. free from lactose, soya and gluten where possible)
  • Ultra-pure, plant-based coating agents (HPMC) and food-safe, light-protected containers
  • Free from unwanted additives such as PEG, silicon dioxide, magnesium stearate & titanium dioxide
  • Premium raw materials from pure substances
  • Regular, independent testing for harmful substances
  • Production in accordance with German quality standards (GMP, HACCP, ISO 9001)

Recommended Consumption

Suggested Use

1 tablet once a day. It is best to take it at least 30 minutes before or 90 minutes after a meal, with 250 ml of still, lukewarm water or, alternatively, with half a freshly squeezed lemon.
Tip: Ideally suited for use as a sublingual tablet, to be taken directly under the tongue.

Notes

Food supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children. Store closed, cool, dry and protected from light.

Content

Ingredients per Daily Dose NRV1
Vitamin B9 Quatrefolic®²
(Folate as 5-MTHF; bioactive)
800 μg 400

1 Nutrient Reference Values for the average adult according to Regulation (EU) No. 1169/2011 (in %).

2 Quatrefolic® is a Registered Trademark of Gnosis S.p.A.

Composition

Filler: microcrystalline cellulose; 5-methyltetrahydrofolate (Quatrefolic®).

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FAQ

We work with the independent laboratory AgroLab, which we commission to perform microbiological and heavy metal tests.

In our microbiological testing, we measure the aerobic mesophilic plate count (total plate count), as well as the levels of Escherichia coli (E. coli), yeasts, Salmonella, molds, and staphylococci.

For heavy metals, we test for arsenic, lead, cadmium, and mercury in accordance with the limit values specified in Regulation (EU) 2023/915.

The optimal duration of use depends on the specific nutrient, your initial situation, diet, and individual requirements.

There is therefore no one-size-fits-all recommendation for how long a product should be taken. For products intended to support nutrient intake over a longer period, use over several weeks to months may be appropriate. In many cases, a period of around three months may be suitable before nutrient status and further requirements are reassessed.

In the case of diagnosed deficiencies, medical conditions, or the use of medication, the use of supplements should be individually discussed with a doctor or qualified healthcare professional.

The optimal time to take a supplement depends on the specific nutrient, individual tolerance, and the composition of the product. However, some ingredients can be particularly well suited to certain times of day or meals.

In the morning

Stimulating ingredients are often preferably taken in the morning or during the first half of the day. These include, for example:

  • Coenzyme Q10
  • Green tea extract
  • Certain B vitamins

Especially for sensitive individuals, it may be advisable to avoid taking stimulating ingredients immediately before bedtime.

Throughout the day

For some nutrients, it may be beneficial to divide the daily amount into several doses.

Water-soluble vitamins such as B vitamins and vitamin C can be taken throughout the day.

Magnesium can also be divided into several doses rather than taking the entire daily amount at once. This may improve tolerance, particularly with higher amounts.

In the evening

Depending on the type of magnesium compound, taking it in the evening may be beneficial. Magnesium glycinate, for example, is often preferably taken in the evening.

In general, however, the best time to take a product also depends on when it is individually best tolerated and can be reliably incorporated into your daily routine.

With a meal

Some nutrients benefit from being taken together with a meal.

Fat-soluble vitamins A, D, E, and K can be taken together and ideally with a meal containing some fat.

Omega-3 fatty acids should also be taken regularly with a meal. Omega-3 oils can be combined well with fat-soluble vitamins.

Many plant-based ingredients can also be taken as part of a meal or together with omega-3 products. However, the optimal timing depends on the specific plant compound and product formulation.

Zinc can cause nausea or stomach discomfort on an empty stomach in some people. If you have a sensitive stomach, it is therefore advisable to take zinc with a meal.

Between meals

Iron is often taken separately from meals, as various foods and beverages can affect its absorption. It is particularly advisable to leave a gap between iron and:

  • Coffee and tea
  • Caffeinated beverages
  • Milk and dairy products
  • Calcium- or mineral-rich supplements

However, if you have a sensitive stomach, iron can also be taken with a meal. In this case, individual tolerance is more important than a theoretically optimal intake situation.

Enzyme supplements vary depending on their intended use: digestive enzymes are generally taken with meals. Products that are specifically intended to be taken between meals may, for example, be taken around 30 minutes before a meal. The product's specific recommended intake should always be followed.

Around exercise

Proteins and amino acids can be taken both before and after training.

If you exercise on an empty stomach, taking them around 30 minutes before training may be beneficial. If you have already eaten a protein-rich meal, you can also plan your protein intake for after training.

In general, ensuring sufficient protein intake throughout the entire day is more important than adhering to a narrow time window around your workout.

If you need this item on a long-term basis and are interested in a discounted subscription, you can find the terms and conditions on the Product Subscription page.

Country-specific information

This item may not be resold in the following countries: Switzerland

Legal notice

This product is for nutritional purposes and therefore does not affect the Heilmittelwerbegesetz (HWG). Good nutritional status is important for your general well-being. All statements made about the product describe properties and physiological effects that may naturally vary among consumers and do not represent any healing or health promises.

Responsible person for the EU

The economic operator based in the EU responsible for this product:
NatuGena GmbH, Münchener Str. 149, 85051 Ingolstadt, Germany, +49 841 90 255 000, info@natugena.de, https://www.natugena.de

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