Fisetin

Fisetin, Quercetin, Spermidin, trans-Resveratrol
Orderable
  • Free of dyes
  • Preservative-free as required by law
  • Lactose-free
  • Vegan
  • Free of anti-caking and binding agents
Product Type
nutritional supplement
Content
90 capsules (size 00) for 30 days
Price Tiers
from 1 Pieces49,95 €
from 3 Pieces44,95 €
from 5 Pieces42,95 €
Quantity

49,95 €

incl. 7% VAT, plus shipping

Delivery time 3–5 workdays
Article number: 2018143
PPN/PZN: 11 20127116 93 (PZN = middle digits)
EAN: 4260633571438
Base price: 1004,42 €per Kilogram
All prices incl. 7% VAT

Fisetin by NatuGena – This formula combines selected plant-based compounds and vitamin B3 in a single product, including fisetin, spermidine, quercetin, green tea extract with EGCG, trans-resveratrol, L-theanine, and vitamin B3. 90 vegan capsules for a 30-day supply.​

  • Fisetin: A plant pigment from the flavonoid group, naturally found in strawberries, apples and tomatoes
  • Spermidine: A naturally occurring polyamine compound, sourced here from wheat germ
  • Quercetin: A polyphenol from the Japanese pagoda tree (Sophora japonica)
  • Green tea extract: Provides natural EGCG, a key catechin in green tea
  • L-theanine: An amino acid found in tea plants, long appreciated in green tea
  • Vitamin B3 (nicotinamide): A bioactive and well-tolerated form of niacin
  • Made in Germany: Exceptional purity and bioavailability for optimal nutrient uptake

More than ever, people today are asking how they can lead active, fulfilling lives in the long term. It's not just about living longer, but about maintaining vitality, performance and joy in life as we age. In the plant world, secondary plant compounds serve a variety of protective functions, like attracting pollinators, repelling pests, or shielding against UV radiation. It's no surprise that scientific interest in how these compounds might also benefit human health is growing.

What makes fisetin a special plant compound?

Fisetin belongs to the flavonoid family of polyphenols. It is found in the smoke tree, which is also known as “fisetinwood”, from which its name is derived. Although present in fruits and vegetables like strawberries, mangos and apples, it naturally occurs only in small amounts. As a polyphenol, fisetin is produced by plants to help protect against environmental stressors.

Why are quercetin, spermidine and resveratrol included in the formula?

The formula is based on the synergistic effects of several natural substances. Quercetin is derived from Sophora japonica, a plant traditionally known for its high flavonoid content. Spermidine is a naturally occurring compound found in all living cells, and in foods such as wheat germ, legumes and mushrooms. In this product, it is sourced from wheat germ extract. Trans-resveratrol is extracted from Japanese knotweed, a plant known for its particularly high resveratrol content.

What does green tea extract provide – and why is L-theanine included?

Green tea is naturally rich in beneficial compounds, including the catechin EGCG (epigallocatechin gallate), a defining component of green tea. The formula also includes L-theanine, an amino acid naturally found in tea leaves.

What is the function of vitamin B3 in this formula?

Vitamin B3 is included in its bioactive and well-tolerated form, nicotinamide. Niacin contributes to normal energy metabolism, supports the function of the nervous system, helps reduce tiredness and fatigue, and contributes to normal psychological function.

Quality

  • No separating agents, binding agents or colourants
  • Free from genetic engineering, nanoparticles and animal testing
  • Hypoallergenic and sensitive formulations (e.g. free from lactose, soya and gluten where possible)
  • Ultra-pure, plant-based coating agents (HPMC) and food-safe, light-protected containers
  • Free from unwanted additives such as PEG, silicon dioxide, magnesium stearate & titanium dioxide
  • Premium raw materials from pure substances
  • Regular, independent testing for harmful substances
  • Production in accordance with German quality standards (GMP, HACCP, ISO 9001)

Recommended Consumption

3 capsules once a day. It is best taken with a high-fat meal with 250 ml of still, lukewarm water or, alternatively, with a teaspoon of omega-3 oil to increase bioavailability.

Notes

Food supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children. Store in a cool, dry place away from light. Do not exceed the recommended daily intake. Should not be consumed on an empty stomach or on the same day as other green tea products.2 Should not be consumed by pregnant or breastfeeding women or children under the age of 18.2
 

2 According to REGULATION (EU) 2022/2340

Content

Ingredients per Daily Dose NRV¹
Fisetin 150 mg  
Quercetin 200 mg  
Wheat Germ Extract 300 mg  
– of which Spermidine 6 mg  
trans-Resveratrol 100 mg  
Green Tea Extract
223 mg
 
– of which Polyphenols 212 mg  
– of which EGCG 100 mg  
L-Theanine 100 mg  
Vitamin B3 (Nicotinamide;
bioactive)
250 mg 1564

1 Nutrient Reference Values for the average adult according to Regulation (EU) No. 1169/2011 (in %).

Composition

Coating agent: Hydroxypropyl Methylcellulose (HPMC); Green Tea Extract, Wheat Germ Extract, Nicotinamide, L-Theanine, Japanese Pagoda Tree Powder, Fisetin, Japanese Knotweed Extract.

 

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FAQ

Most of our capsules can be opened without any concerns. The contents can be stirred into yogurt, plant-based yogurt, applesauce, smoothies, or juice, for example.

One of the reasons we encapsulate the ingredients is to keep their sometimes intense natural taste and smell as neutral as possible. When opened, the taste and smell may therefore be more noticeable.

Did you know? Our capsules can be easily opened by gently twisting them.

Please do not open: enteric-coated capsules

For certain bacterial and enzyme products, we use enteric-coated capsules. These should not be opened, as doing so may alter the intended release profile.

These include, for example:

  • Bacterial preparations, such as HistaBakt, MakroAktiv, and BactoGena 21+2
  • Enzyme products, such as N-Zymarase® Intest and N-Zymarase® Inflam. Exception: N-Zymarase Komplex contains betaine HCl, which is intended to take effect in the stomach; therefore, it does not have an enteric-coated capsule shell and can be opened
  • Soft capsules with liquid contents, such as omega-3 capsules, are also not intended to be opened. In this case, you can switch to the liquid oil instead.

If you have any questions, please contact our advisory team at info@natugena.de.

From the very beginning, NatuGena has used exceptionally pure, plant-based HPMC capsules in the majority of its products. HPMC stands for hydroxypropyl methylcellulose and is made from plant-based cellulose.

Unlike many HPMC capsules commonly available on the market, the coating agents we use contain no carrageenan or PEG. Although they are more expensive, they meet our high standards for a carefully selected and transparent product composition.

Our plant-based HPMC capsules are:
  • 100% plant-based cellulose (HPMC)
  • Carrageenan-free
  • PEG-free
  • Gelatin-free
  • GMO-free
  • Free of allergens and irritants
What types of capsule shells are used in omega-3 products?

Special softgels are required for liquid oils. Our classic omega-3 capsules therefore contain a coating made from gelatin and glycerin and are not vegan.

In our vegan omega-3 capsules made from algae oil, the coating consists of glycerin and modified cornstarch and contains no gelatin. This makes these capsules suitable for a vegan diet.

The exact composition of each coating agent is clearly listed in the ingredients list.

It All Comes Down to the Composition

Conventional capsule shells may contain technical additives—such as anti-caking agents, release agents, or binders—due to the manufacturing process. These components aren’t always immediately apparent, as certain processing aids aren’t required to be listed in the ingredients list.

People who take several dietary supplements daily, in particular, regularly ingest not only the actual ingredients but also the respective capsule shells. That is why at NatuGena, we pay close attention not only to the quality of the nutrients and plant-based ingredients contained in our products but also to the composition and processing of the capsule shells. For us, transparency, purity, and quality go hand in hand.

Most of the NatuGena capsule products are size 00 (8,2 × 23,3 mm) to 0 (7,3 × 21,2 mm). Information on the capsule sizes of individual products can be found on the relevant product page or by contacting info@natugena.de

NatuGena® capsule sizes – for comparison and understanding.
Size 000 Size 00 Size 0 Size 1 Size 2 Size 3
9,5 × 26,1 mm 8,2 × 23,3 mm 7,3 × 21,2 mm 6,6 × 19,0 mm 6,1 × 17,3 mm 5,6 × 15,4 mm
z. B. Lysin & Vitamin C,
Monacolin K 3
z. B. Magnesia 7+1,
Mitochondrien­Aktivator 44+14,
HeparAktiv
z. B. ZellEnergie,
MultiVegan,
Astaxanthin
z. B. HistaBakt,
Bor,
Bioaktiver B-Komplex
not in use z. B. Kupfer,
Lipo­Vitamine 10 000,
Mangan-Komplex

We work with the independent laboratory AgroLab, which we commission to perform microbiological and heavy metal tests.

In our microbiological testing, we measure the aerobic mesophilic plate count (total plate count), as well as the levels of Escherichia coli (E. coli), yeasts, Salmonella, molds, and staphylococci.

For heavy metals, we test for arsenic, lead, cadmium, and mercury in accordance with the limit values specified in Regulation (EU) 2023/915.

The optimal duration of use depends on the specific nutrient, your initial situation, diet, and individual requirements.

There is therefore no one-size-fits-all recommendation for how long a product should be taken. For products intended to support nutrient intake over a longer period, use over several weeks to months may be appropriate. In many cases, a period of around three months may be suitable before nutrient status and further requirements are reassessed.

In the case of diagnosed deficiencies, medical conditions, or the use of medication, the use of supplements should be individually discussed with a doctor or qualified healthcare professional.

The optimal time to take a supplement depends on the specific nutrient, individual tolerance, and the composition of the product. However, some ingredients can be particularly well suited to certain times of day or meals.

In the morning

Stimulating ingredients are often preferably taken in the morning or during the first half of the day. These include, for example:

  • Coenzyme Q10
  • Green tea extract
  • Certain B vitamins

Especially for sensitive individuals, it may be advisable to avoid taking stimulating ingredients immediately before bedtime.

Throughout the day

For some nutrients, it may be beneficial to divide the daily amount into several doses.

Water-soluble vitamins such as B vitamins and vitamin C can be taken throughout the day.

Magnesium can also be divided into several doses rather than taking the entire daily amount at once. This may improve tolerance, particularly with higher amounts.

In the evening

Depending on the type of magnesium compound, taking it in the evening may be beneficial. Magnesium glycinate, for example, is often preferably taken in the evening.

In general, however, the best time to take a product also depends on when it is individually best tolerated and can be reliably incorporated into your daily routine.

With a meal

Some nutrients benefit from being taken together with a meal.

Fat-soluble vitamins A, D, E, and K can be taken together and ideally with a meal containing some fat.

Omega-3 fatty acids should also be taken regularly with a meal. Omega-3 oils can be combined well with fat-soluble vitamins.

Many plant-based ingredients can also be taken as part of a meal or together with omega-3 products. However, the optimal timing depends on the specific plant compound and product formulation.

Zinc can cause nausea or stomach discomfort on an empty stomach in some people. If you have a sensitive stomach, it is therefore advisable to take zinc with a meal.

Between meals

Iron is often taken separately from meals, as various foods and beverages can affect its absorption. It is particularly advisable to leave a gap between iron and:

  • Coffee and tea
  • Caffeinated beverages
  • Milk and dairy products
  • Calcium- or mineral-rich supplements

However, if you have a sensitive stomach, iron can also be taken with a meal. In this case, individual tolerance is more important than a theoretically optimal intake situation.

Enzyme supplements vary depending on their intended use: digestive enzymes are generally taken with meals. Products that are specifically intended to be taken between meals may, for example, be taken around 30 minutes before a meal. The product's specific recommended intake should always be followed.

Around exercise

Proteins and amino acids can be taken both before and after training.

If you exercise on an empty stomach, taking them around 30 minutes before training may be beneficial. If you have already eaten a protein-rich meal, you can also plan your protein intake for after training.

In general, ensuring sufficient protein intake throughout the entire day is more important than adhering to a narrow time window around your workout.

If you need this item on a long-term basis and are interested in a discounted subscription, you can find the terms and conditions on the Product Subscription page.

Country-specific information

This item may not be resold in the following countries: Switzerland

Legal notice

This product is for nutritional purposes and therefore does not affect the Heilmittelwerbegesetz (HWG). Good nutritional status is important for your general well-being. All statements made about the product describe properties and physiological effects that may naturally vary among consumers and do not represent any healing or health promises.

Responsible person for the EU

The economic operator based in the EU responsible for this product:
NatuGena GmbH, Münchener Str. 149, 85051 Ingolstadt, Germany, +49 841 90 255 000, info@natugena.de, https://www.natugena.de

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