N-Zymarase® Gluten
Tolerase® G Enzymes, Fennel, Caraway & Ginger
Orderable
- Free of dyes
- Preservative-free as required by law
- Lactose-free
- Vegan
- Free of anti-caking and binding agents
| Price Tiers |
| from 1 Pieces | 39,95 € |
| from 3 Pieces | 35,95 € |
| from 5 Pieces | 33,95 € |
NatuGena N-Zymarase Gluten – Contains the patented Tolerase® G, enriched with natural extracts of fennel, caraway and ginger, as well as the nutrients iron, calcium, vitamin B2 and vitamin B7. 90 vegan capsules for a 30-day supply.
- Tolerase® G: Patented enzyme product to complement plant extracts
- Fennel extract: The small yellow seeds of fennel are a popular culinary spice
- Caraway extract: Spice plant with a distinctive flavour
- Ginger extract: Aromatic root originating from Southeast Asia
- B vitamins: Vitamin B2 and vitamin B7 in bioactive forms
- Plant-based: Suitable for vegetarians and vegans
- Produced in Germany: Exceptional purity and bioavailability for optimal nutrient uptake

Many people experience recurring discomfort such as bloating, flatulence or general unease after consuming wheat, rye or barley. Gluten is a protein found in these grains and, in cases of gluten sensitivity, may not be processed by the body as usual. Maintaining a consistent dietary routine can be challenging, especially during spontaneous restaurant visits, travel or special occasions.
What does the N-Zymarase Gluten complex contain?
NatuGena N-Zymarase Gluten combines the patented enzyme Tolerase® G, developed by DSM, with carefully selected plant extracts and bioactive nutrients. Tolerase® G is a specially processed enzyme derived from the food-grade fungus Aspergillus niger.

Which plant extracts are included?
Fennel, caraway and ginger have been valued for centuries in culinary traditions and herbal practices.
Fennel is an aromatic plant native to the Mediterranean region and is known for its versatile culinary uses. Its seeds have a distinctive aroma.
Caraway belongs to the umbellifer family and is appreciated for its spicy, slightly sweet flavour profile.
Ginger originates from Southeast Asia and is particularly popular for its mildly pungent, lemony taste. The root is used fresh, dried or ground in cooking. The plant prefers moist, well-drained soils and a warm, shaded climate. Ginger is valued worldwide across many culinary cultures for its versatility.
How do the nutrients in N-Zymarase Gluten contribute?
Calcium contributes to the normal function of digestive enzymes and to a normal energy-yielding metabolism.
Iron supports the normal formation of red blood cells and normal oxygen transport in the body.
Vitamin B2 contributes to a normal energy-yielding metabolism and helps protect cells from oxidative stress.
Vitamin B7 also contributes to a normal energy-yielding metabolism and supports macronutrient metabolism as well as the normal function of the nervous system.
Quality
- No separating agents, binding agents or colourants
- Free from genetic engineering, nanoparticles and animal testing
- Hypoallergenic and sensitive formulations (e.g. free from lactose, soya and gluten where possible)
- Ultra-pure, plant-based coating agents (HPMC) and food-safe, light-protected containers
- Free from unwanted additives such as PEG, silicon dioxide, magnesium stearate & titanium dioxide
- Premium raw materials from pure substances
- Regular, independent testing for harmful substances
- Production in accordance with German quality standards (GMP, HACCP, ISO 9001)
Recommended Consumption
3 capsules once a day or, alternatively, 1 capsule each in the morning, at lunchtime and in the evening. It is best to take them with a meal and 250 ml of still, lukewarm water.
Notes
Food supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children. Store in a cool, dry place away from light. Do not exceed the recommended daily intake. Tolerase® G is not intended as a substitute for a gluten-free diet. Tolerase® G is not intended for the treatment or prevention of coeliac disease.
Content
| Ingredients per | daily dose | NRV¹ |
|---|---|---|
| Tolerase®² G-Enzymes | 320 mg | |
| Fennel extract (4:1) | 220 mg | |
| Caraway extract (10:1) | 180 mg | |
| Ginger extract | 150 mg | |
| – of which gingerols | 7,5 mg | |
| Calcium | 240 mg | 30 |
| Iron | 14 mg | 100 |
| Vitamin B2 (R5P; bioactive) | 1,4 mg | 100 |
| Vitamin B7 (D-biotin; bioactive) | 50 μg | 100 |
1 Reference intakes for the average adult according to Regulation (EU) No 1169/2011 (in %).
2 Tolerase® G is a trademark of DSM.
Composition
Tricalcium citrate, coating agent: hydroxypropyl methylcellulose (HPMC); Prolyloligopeptidase (Tolerase® G), fennel extract (4:1), caraway extract (10:1), ginger extract, ferrous fumarate, riboflavin-5-phosphate, D-biotin.
Blog Articles
FAQ
Which enzyme product is right for which need?
The N-Zymarase products differ primarily in terms of when they should be taken and the specific focus of their formulation. While N-Zymarase Complex and N-Zymarase Intest are designed to support digestion after a meal, N-Zymarase Fructose and N-Zymarase Gluten complement these products for specific needs. N-Zymarase Inflam holds a special place within the product family.
Which is a classic digestive enzyme product to take with a meal?
For a classic digestive enzyme complex, the following three enzymes form a good foundation:
- Bromelain for breaking down proteins
- Papain to support protein digestion
- Lipase for breaking down dietary fats
All three enzymes are included in the following products. Here’s a quick overview of the differences:
- N-Zymarase Complex - 16 enzymes plus betaine HCl - an exceptionally broad spectrum of enzymes for the digestion of carbohydrates, fats, and proteins
- N-Zymarase Intest - 8 enzymes - comprehensive digestive support with a focus on fat digestion
- Bromelain 1200 - 3 enzymes - focuses on highly active bromelain
When are N-Zymarase Gluten and N-Zymarase Fructose recommended?
N-Zymarase Fructose is a specialized product for meals where fructose is the primary focus. It contains the enzyme glucose isomerase, which converts fructose into glucose, supplemented by L-glutamine, vitamins B7 and B9, and zinc, among other ingredients; therefore, it does not replace a broad-spectrum digestive enzyme complex but rather specifically complements it.
Depending on the composition of the meal, N-Zymarase Fructose can be combined with N-Zymarase Complex or N-Zymarase Intest.
N-Zymarase Gluten is designed to enzymatically break down gluten-containing components of a meal, featuring the specific digestive enzyme “Tolerase G” for breaking down gluten, as well as fennel, caraway, and ginger. This product is not a substitute for a gluten-free diet in cases of diagnosed celiac disease.
If needed, N-Zymarase Gluten can be taken with a meal in combination with N-Zymarase Complex or N-Zymarase Intest.
How does N-Zymarase Inflam differ from digestive enzymes?
N-Zymarase Inflam is not designed as a traditional digestive enzyme complex to be taken with meals. In addition to bromelain and papain, it contains the specific enzymes trypsin and rutin. It is recommended to take N-Zymarase Inflam between meals, as this allows the enzymes to be distributed more effectively throughout the body.
NatuGena’s enzyme supplements for the digestion of proteins, carbohydrates, gluten, lactose, and other dietary challenges—for a healthy gut!
- N-Zymarase Complex: 16 enzymes plus betaine HCl—for a particularly broad spectrum of enzymes to take with meals.
- N-Zymarase Intest: 8 digestive enzymes—compact support for the digestion of protein, fat, and carbohydrates.
- Bromelain 1200: Bromelain, papain, and lipase—with a focus on highly active bromelain.
- N-Zymarase Fructose: a targeted supplement for meals containing fructose.
- N-Zymarase Gluten: with Tolerase® G for the enzymatic breakdown of gluten. Not suitable for people with celiac disease.
- N-Zymarase Inflam: bromelain, papain, trypsin, and rutin—not a traditional digestive enzyme; take between meals.
Each enzyme has its own optimal units of measurement. The enzymatic activity of bromelain, for example, is expressed in GDU (Gelatin Digesting Units). This corresponds to the ability to digest gelatin under controlled experimental conditions.
Another example is provided by the so-called HUT units (Hemoglobin Unit Tyrosine base) of the enzyme protease. These units measure the amount of enzyme required to digest a specific amount of tyrosine-releasing peptide bonds from a hemoglobin-containing substrate under standardized conditions.
To provide you with the most meaningful information possible regarding the individual enzymatic activities, the units of measurement for each enzyme may differ from one another.
Unfortunately, it is not possible to convert enzyme units into other units, as they are determined experimentally.
NatuGena’s enzyme supplements for the digestion of proteins, carbohydrates, gluten, lactose, and other challenges—generally for a healthy gut!
No. N-Zymarase Gluten is not a substitute for a low-gluten or gluten-free diet. It is intended as a supplementary aid for people with gluten sensitivity when small amounts of gluten cannot be reliably avoided—for example, while on vacation or in breading. The product is not suitable for people diagnosed with celiac disease; a strictly gluten-free diet remains necessary.
Most of our capsules can be opened without any concerns. The contents can be stirred into yogurt, plant-based yogurt, applesauce, smoothies, or juice, for example.
One of the reasons we encapsulate the ingredients is to keep their sometimes intense natural taste and smell as neutral as possible. When opened, the taste and smell may therefore be more noticeable.
Did you know? Our capsules can be easily opened by gently twisting them.
Please do not open: enteric-coated capsules
For certain bacterial and enzyme products, we use enteric-coated capsules. These should not be opened, as doing so may alter the intended release profile.
These include, for example:
- Bacterial preparations, such as HistaBakt, MakroAktiv, and BactoGena 21+2
- Enzyme products, such as N-Zymarase® Intest and N-Zymarase® Inflam. Exception: N-Zymarase Komplex contains betaine HCl, which is intended to take effect in the stomach; therefore, it does not have an enteric-coated capsule shell and can be opened
- Soft capsules with liquid contents, such as omega-3 capsules, are also not intended to be opened. In this case, you can switch to the liquid oil instead.
If you have any questions, please contact our advisory team at info@natugena.de.
From the very beginning, NatuGena has used exceptionally pure, plant-based HPMC capsules in the majority of its products. HPMC stands for hydroxypropyl methylcellulose and is made from plant-based cellulose.
Unlike many HPMC capsules commonly available on the market, the coating agents we use contain no carrageenan or PEG. Although they are more expensive, they meet our high standards for a carefully selected and transparent product composition.
Our plant-based HPMC capsules are:
- 100% plant-based cellulose (HPMC)
- Carrageenan-free
- PEG-free
- Gelatin-free
- GMO-free
- Free of allergens and irritants
What types of capsule shells are used in omega-3 products?
Special softgels are required for liquid oils. Our classic omega-3 capsules therefore contain a coating made from gelatin and glycerin and are not vegan.
In our vegan omega-3 capsules made from algae oil, the coating consists of glycerin and modified cornstarch and contains no gelatin. This makes these capsules suitable for a vegan diet.
The exact composition of each coating agent is clearly listed in the ingredients list.
It All Comes Down to the Composition
Conventional capsule shells may contain technical additives—such as anti-caking agents, release agents, or binders—due to the manufacturing process. These components aren’t always immediately apparent, as certain processing aids aren’t required to be listed in the ingredients list.
Most of the NatuGena capsule products are size 00 (8,2 × 23,3 mm) to 0 (7,3 × 21,2 mm). Information on the capsule sizes of individual products can be found on the relevant product page or by contacting info@natugena.de
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
|---|---|---|---|---|---|
| 9,5 × 26,1 mm | 8,2 × 23,3 mm | 7,3 × 21,2 mm | 6,6 × 19,0 mm | 6,1 × 17,3 mm | 5,6 × 15,4 mm |
| z. B. Lysin & Vitamin C, Monacolin K 3 |
z. B. Magnesia 7+1, MitochondrienAktivator 44+14, HeparAktiv |
z. B. ZellEnergie, MultiVegan, Astaxanthin |
z. B. HistaBakt, Bor, Bioaktiver B-Komplex |
not in use | z. B. Kupfer, LipoVitamine 10 000, Mangan-Komplex |
We work with the independent laboratory AgroLab, which we commission to perform microbiological and heavy metal tests.
In our microbiological testing, we measure the aerobic mesophilic plate count (total plate count), as well as the levels of Escherichia coli (E. coli), yeasts, Salmonella, molds, and staphylococci.
For heavy metals, we test for arsenic, lead, cadmium, and mercury in accordance with the limit values specified in Regulation (EU) 2023/915.
The optimal duration of use depends on the specific nutrient, your initial situation, diet, and individual requirements.
There is therefore no one-size-fits-all recommendation for how long a product should be taken. For products intended to support nutrient intake over a longer period, use over several weeks to months may be appropriate. In many cases, a period of around three months may be suitable before nutrient status and further requirements are reassessed.
In the case of diagnosed deficiencies, medical conditions, or the use of medication, the use of supplements should be individually discussed with a doctor or qualified healthcare professional.
The optimal time to take a supplement depends on the specific nutrient, individual tolerance, and the composition of the product. However, some ingredients can be particularly well suited to certain times of day or meals.
In the morning
Stimulating ingredients are often preferably taken in the morning or during the first half of the day. These include, for example:
- Coenzyme Q10
- Green tea extract
- Certain B vitamins
Especially for sensitive individuals, it may be advisable to avoid taking stimulating ingredients immediately before bedtime.
Throughout the day
For some nutrients, it may be beneficial to divide the daily amount into several doses.
Water-soluble vitamins such as B vitamins and vitamin C can be taken throughout the day.
Magnesium can also be divided into several doses rather than taking the entire daily amount at once. This may improve tolerance, particularly with higher amounts.
In the evening
Depending on the type of magnesium compound, taking it in the evening may be beneficial. Magnesium glycinate, for example, is often preferably taken in the evening.
In general, however, the best time to take a product also depends on when it is individually best tolerated and can be reliably incorporated into your daily routine.
With a meal
Some nutrients benefit from being taken together with a meal.
Fat-soluble vitamins A, D, E, and K can be taken together and ideally with a meal containing some fat.
Omega-3 fatty acids should also be taken regularly with a meal. Omega-3 oils can be combined well with fat-soluble vitamins.
Many plant-based ingredients can also be taken as part of a meal or together with omega-3 products. However, the optimal timing depends on the specific plant compound and product formulation.
Zinc can cause nausea or stomach discomfort on an empty stomach in some people. If you have a sensitive stomach, it is therefore advisable to take zinc with a meal.
Between meals
Iron is often taken separately from meals, as various foods and beverages can affect its absorption. It is particularly advisable to leave a gap between iron and:
- Coffee and tea
- Caffeinated beverages
- Milk and dairy products
- Calcium- or mineral-rich supplements
However, if you have a sensitive stomach, iron can also be taken with a meal. In this case, individual tolerance is more important than a theoretically optimal intake situation.
Enzyme supplements vary depending on their intended use: digestive enzymes are generally taken with meals. Products that are specifically intended to be taken between meals may, for example, be taken around 30 minutes before a meal. The product's specific recommended intake should always be followed.
Around exercise
Proteins and amino acids can be taken both before and after training.
If you exercise on an empty stomach, taking them around 30 minutes before training may be beneficial. If you have already eaten a protein-rich meal, you can also plan your protein intake for after training.
In general, ensuring sufficient protein intake throughout the entire day is more important than adhering to a narrow time window around your workout.
If you need this item on a long-term basis and are interested in a discounted subscription, you can find the terms and conditions on the Product Subscription page.
Legal notice
This product is for nutritional purposes and therefore does not affect the Heilmittelwerbegesetz (HWG). Good nutritional status is important for your general well-being. All statements made about the product describe properties and physiological effects that may naturally vary among consumers and do not represent any healing or health promises.
Responsible person for the EU
The economic operator based in the EU responsible for this product:
NatuGena GmbH, Münchener Str. 149, 85051 Ingolstadt, Germany,
+49 841 90 255 000, info@natugena.de, https://www.natugena.de





